Date: April 2022.
Source: Skin Health and Disease, e132,
Background: The diagnosis of Scleroderma En Coup de Sabre (ECDS)/ Parry Romberg Syndrome (PRS) is mainly based on characteristic clinical findings. Methods to objectively monitor the course of the disease in a standardized way are lacking.
Objective: This descriptive, retrospective, single centre cohort study aims to describe the contribution of 3D photographs in the assessment of the degree of facial asymmetry changes over time in growing children and adolescents with ECDS and PRS.
Materials and Methods: Six patients diagnosed with ECDS/PRS, with a follow‐up period of at least 24 months and at least three 3D photographs were included. Mirroring these 3D photographs was automatically performed using surface‐based matching to generate a colour‐coded distance map, illustrating the inter‐surface distance and thereby asymmetry between the original and mirrored 3D photographs. The percentage of absolute distances between the original and mirrored 3D photograph were calculated.
Results: In two patients, impressive decreases in the percentages of absolute distance levels over time were found, whereas the other patients did not show progression of asymmetry over time.
Conclusions: This study shows the potential of 3D stereophotogrammetry as an objective tool to measure disease activity over time in patients with ECDS/PRS.

Article: 3D stereophotogrammetry in children and adolescents with Scleroderma En Coup De Sabre/Parry‐Romberg Syndrome: Description of a novel method for monitoring disease progression.
Authors: Rutger ter Horst, Thomas JJ Maal, Martien JJ de Koning, Jorre S Mertens, Ellen JH Schatorjé, Esther P Hoppenreijs, Marieke MB Seyger, Department of Oral and Maxillofacial Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.