Date: July 2023.
Source: Journal of Neurosurgery: Pediatrics, 32(4), 455-463. https://doi.org/10.3171/2023.5.PEDS2382.
Objective: Several studies have compared perioperative parameters and early postoperative morphology between endoscope-assisted strip craniectomy with orthotic therapy (endoscopic repair) and cranial vault remodeling (open repair). To extend these results, the authors evaluated school-age anthropometric outcomes after these techniques across three institutions.
Materials and Methods: School-aged children (age range 4–18 years) with previously corrected isolated sagittal craniosynostosis were enrolled. Upon inclusion, 3D photographs and patient-reported outcomes were obtained, and the cephalic index and head circumference z-scores were calculated. Analyses of covariance models controlling for baseline differences and a priori covariates were performed.
Results: Eighty-one participants (median [range] age 7 [4–15] years) were included. The mean (95% CI) school-age cephalic index was significantly higher in the endoscopic cohort, though within the normal range for both groups (endoscopic 78% [77%–79%] vs open 76% [74%–77%], p = 0.027). The mean change in the cephalic index from pre-operation to school age was significantly greater in the endoscopic group (9% [7%–11%] vs open 3% [1%–5%], p < 0.001). Compared to preoperative measurements, mean school-age head circumference z-scores decreased significantly more in the open cohort (−1.6 [−2.2 to −1.0] vs endoscopic −0.3 [−0.8 to −0.2], p = 0.002). Patient-reported levels of stigma were within the normal limits for both groups.
Conclusions: Endoscopic and open repair techniques effectively normalize school-age anthropometric outcomes. However, endoscopic repair produces a clinically meaningful and significantly greater improvement in the school-age cephalic index, with maintenance of head growth. These findings demonstrate the importance of early referral by pediatricians and inform treatment decisions.
In Brief: The authors’ multi-institutional investigation compared school-age anthropometric measurements obtained on 3D photographs and patient-reported outcomes among patients who underwent repair of isolated sagittal craniosynostosis with either calvarial vault remodeling or endoscopic strip craniectomy. The authors found that, at school age, endoscopic repair produced a clinically meaningful and significantly greater improvement in anthropometric outcomes compared with open repair. Referral to a craniofacial surgeon before 6 months of age is essential to allow patients to undergo this repair technique.
Article: School-age anthropometric and patient-reported outcomes after open or endoscopic repair of sagittal craniosynostosis.
Authors: AR Fotouhi, KB Patel, GB Skolnick, CM Merrill, KM Hofmann, E Mantilla-Rivas, BR Collett, VD Allhusen, SD Naidoo, GF Rogers, RF Keating, MD Smyth, SN Magge. Department of Surgery, Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, MO; Children’s Hospital of Orange County, Orange, CA; Children’s National Hospital, Washington, DC, USA.