Date: March 2026.
Source: The Cleft Palate Craniofacial Journal, DOI: 10.1177/10556656261431485.
Objective: To compare 3D mandibular morphometrics of neonates with Pierre Robin sequence (PRS) to age-matched controls, establish normative data, and better understand anatomic differences.
Materials and Methods: Retrospective case-control study — 25 neonates with non-syndromic PRS vs. 25 age-matched controls.
Results: Asymmetry in PRS body length was significantly higher than in control mandibles (p=.006). PRS measurements larger than controls included intercondylar distance, intergonial distance, pogonion-interdental distance, ramus height, and ramus-height-to-body-length ratio; PRS measurements smaller than controls included intercondylar angle, body length, and effective mandibular length (all p<.05 or better).
Conclusions: Micrognathia in severe PRS is constituted by a wide and antero-posteriorly short mandible for its height, with implications for mandibular distraction osteogenesis (MDO) surgical planning.

Article: Evaluating 3D Morphometrics for Assessing Micrognathia in Neonates with Severe Pierre Robin Sequence: A Case-Control Study.
Authors: Sahejbir S Bhatia, Paul W Hung, Alexander E Velazquez, Kayla Prezelski, Lucas M Harrison, Timothy Booth, Rami R Hallac, Alex A Kane, Paymon Sanati-Mehrizy. Department of Plastic Surgery, University of Texas Southwestern Medical Center; Analytical Imaging and Modeling Center, Children’s Health Medical Center, Dallas, TX, USA.

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