Monitoring of Therapy for Mucopolysaccharidosis Type I Using Dysmorphometric Facial Phenotypic Signatures. Stefanie Kung, M Walters, P Claes, P LeSouef, J Goldblatt, A Martin, S Balasubramaniam, G Baynam.

Date: March 2015. Source: JIMD Reports 2015, Springer. Abstract: There is a pattern of progressive facial dysmorphology in mucopolysaccharidosis type I (MPS I). Advances in 3D facial imaging have facilitated the development of tools, including dysmorphometrics, to objectively and precisely detect these facial phenotypes. Therefore, we investigated the application of dysmorphometrics as a noninvasive therapy-monitoring…

Prenatal sex hormones, digit ratio, and face shape in adult males. SM Weinberg, TE Parsons, ZD Raffensperger.

Date: February 2015. Source: Orthodontics & Craniofacial Research, 18(1):21-6. Objectives: Several reports have demonstrated a relationship between second to fourth digit ratio (2D:4D) and facial shape, suggesting that prenatal sex hormones play a role in the development of the craniofacial complex. Using 3D surface imaging and geometric morphometrics, we test the hypothesis that decreased digit…

Regional facial asymmetries in unilateral orofacial clefts. MA Kuijpers, DJ Desmedt, RM Nada, SJ Bergé, PS Fudalej, TJJ Maal.

Date: February 2015. Source: The European Journal of Orthodontics. Objectives: Assess facial asymmetry in subjects with unilateral cleft lip (UCL), unilateral cleft lip and alveolus (UCLA), and unilateral cleft lip, alveolus, and palate (UCLP), and to evaluate which area of the face is most asymmetrical. Methods: Standardized three-dimensional facial images of 58 patients (9 UCL,…

Monobloc Le Fort III Distraction Osteogenesis for Correction of Severe Fronto-orbital and Midface Hypoplasia in Pediatric Crouzon Syndrome. F Hariri, LK Cheung, ZA Rahman, V Mathaneswaran, D Ganesan.

Date: February 2015. Source: The Cleft Palate-Craniofacial Journal. Abstract: In severe syndromic craniosynostosis, distraction osteogenesis (DO) provides superior segmental advancement and allows progressive clinical monitoring to ensure that adequate skeletal expansion is achieved. We report two cases of Crouzon syndrome involving a 3-year-old boy and a 4-year-old girl, who were both treated with monobloc Le…

Three-dimensional changes in nose and upper lip volume after orthognathic surgery. B van Loon, N van Heerbeek, F Bierenbroodspot, L Verhamme, T Xi, MJJ de Koning, KJAO Ingels, SJ Bergé, TJJ Maal.

Date: January 2015 Source: International Journal of Oral and Maxillofacial Surgery, 44(1):83-9. Abstract: Orthognathic surgery aims to improve both the function and facial appearance of the patient. Translation of the maxillomandibular complex for correction of malocclusion is always followed by changes to the covering soft tissues, especially the nose and lips. The purpose of this study…

In-vivo quantification of human breast deformation associated with the position change from supine to upright. H Khatam, GP Reece, MC Fingeret, MK Markey, K Ravi-Chandar.

Date: January 2015. Source: Medical Engineering and Physics, 37(1):13-22. Abstract: Stereophotographic imaging and digital image correlation are used to determine the variation of breast skin deformation as the subject orientation is altered from supine to upright. A change in subject’s position from supine to upright can result in significant stretches in some parts of the…

A New Objective Automatic Computational Framework for Evaluating and Visualizing the Results of Infant Cranial Surgery. B Yuan, D Khechoyan, R Goldman.

Date: December 14-16, 2014. Source: 2014 ASE BigData/SocialInformatics/PASSAT/BioMedCom 2014 Conference, Harvard University. Abstract: We describe a novel automatic computational framework for evaluating and visualizing the results of infant cranial surgeries. We begin by capturing a 3D triangle mesh of the subject’s head using a 3dMD camera. Our framework includes a mesh decimation algorithm to simplify…

Reliability and validity of measurements of facial swelling with a stereophotogrammetry optical three-dimensional scanner. WJ van der Meer, PU Dijkstra, A Visser, A Vissink, Y Ren.

Date: December 2014 Source: British Journal of Oral Maxillofacial Surgery, 52(10):922-7. Abstract: Volume changes in facial morphology can be assessed using the 3dMDface® stereo-optical 3-dimensional scanner, which uses visible light and has a short scanning time. Its reliability and validity have not to our knowledge been investigated for the assessment of facial swelling. Our aim…

Nasal changes after orthognathic surgery for patients with prognathism and Class III malocclusion: Analysis using three-dimensional photogrammetry. S Worasakwutiphong; YF Chuang; HW Chang; HH Lin; PJ Lin; LJ Lo.

Date: December 2014. Source: Journal of the Formosan Medical Association. Background/Purpose. Orthognathic surgery alters the position of maxilla and mandible, and consequently changes the nasal shape. The nasal change remains a concern to Asian patients. The aim of this study was to measure the nasal changes using a novel three-dimensional photographic imaging method. Methods. A…