Immune function during early adolescence positively predicts adult facial sexual dimorphism in both men and women. YZ Foo, LW Simmons, DI Perrett et al.

Date: February 2020 (Online). Source: Evolution and Human Behavior. https://doi.org/10.1016/j.evolhumbehav.2020.02.002. Abstract: Evolutionary theories suggest that humans prefer sexual dimorphism in faces because masculinity in men and femininity in women may be an indicator of immune function during development. In particular, the immunocompetence handicap hypothesis proposes that sexual dimorphism indicates good immune function during development because the…

A broad autism phenotype expressed in facial morphology. DW Tan, MT Maybery, SZ Gilani et al.

Date: January 2020. Source: Translational Psychiatry, Volume 10, Article No. 7. Abstract: Autism spectrum disorder is a heritable neurodevelopmental condition diagnosed based on social and communication differences. There is strong evidence that cognitive and behavioural changes associated with clinical autism aggregate with biological relatives but in milder form, commonly referred to as the ‘broad autism…

Sex‐specific variation in facial masculinity/ femininity associated with autistic traits in the general population. DW Tan, MT Maybery, L Ewing, JX Tay, PR Eastwood, AJO Whitehouse.

Date: December 2019. Source: British Journal Psychology. doi: 10.1111/bjop.12436. (Online) Abstract: Reports linking prenatal testosterone exposure to autistic traits and to a masculinized face structure have motivated research investigating whether autism is associated with facial masculinization. This association has been reported with greater consistency for females than for males, in studies comparing groups with high…

An Automated CNN-based 3D Anatomical Landmark Detection Method to Facilitate Surface-Based 3D Facial Shape Analysis. R Huang, M Suttie, JA Noble.

Date: October 2019. Source: Greenspan H. et al. (eds) Uncertainty for Safe Utilization of Machine Learning in Medical Imaging and Clinical Image-Based Procedures. CLIP 2019, UNSURE 2019. Lecture Notes in Computer Science, vol 11840. Springer, Cham. Abstract: Maternal alcohol consumption during pregnancy can lead to a wide range of physical and neurodevelopmental problems, collectively known…

Methods and Challenges in a Cohort Study of Infants and Toddlers With Craniofacial Microsomia: The Clock Study. DV Luquetti, ML Speltz, ER Wallace, B Siebold, BR Collett, AF Drake, … CL Heike (2019).

Date: August 2019. Source: The Cleft Palate-Craniofacial Journal, Volume: 56 issue: 7, page(s): 877-889. Objective: The Craniofacial microsomia: Longitudinal Outcomes in Children pre-Kindergarten (CLOCK) study is a longitudinal cohort study of neurobehavioral outcomes in infants and toddlers with craniofacial microsomia (CFM). In this article, we review the data collection and methods used to characterize this…

Increased facial asymmetry in autism spectrum conditions is associated with symptom presentation. M Boutrus, SZ Gilani, GA Alvares, MT Maybery, DW Tan, A Mian, AJO Whitehouse.

Date: June 2019. Source: Autism Research. ©2019 International Society for Autism Research, Wiley Periodicals, Inc. Abstract: A key research priority in the study of autism spectrum conditions (ASC) is the discovery of biological markers that may help to identify and elucidate etiologically distinct subgroups. One physical marker that has received increasing research attention is facial…

EDAR, LYPLAL1, PRDM16, PAX3, DKK1, TNFSF12, CACNA2D3, and SUPT3H gene variants influence facial morphology in a Eurasian population. Y Li, W Zhao, D Li et al.

Date: April 2019. Source: Human Genetics 138, 681–689 (2019). https://doi.org/10.1007/s00439-019-02023-7. Abstract: In human society, the facial surface is visible and recognizable based on the facial shape variation which represents a set of highly polygenic and correlated complex traits. Understanding the genetic basis underlying facial shape traits has important implications in population genetics, developmental biology, and…

Linking the Expression of Facial Shape and BMI via the Hippo Signaling Pathway. S Ali, DE Ehrlich, LM Moreno Uribe, BA Amendt, MK Lee, JR Shaffer, ML Marazita, SM Weinberg, SF Miller.

Date: April 2019. Source: The FASEB Journal, Vol. 33, No. 1_supplement. Abstract: Obesity rates have more than tripled in children and adolescents in recent years. While many studies have examined the relationship between obesity and chronic illnesses, the impact of obesity on craniofacial form is less understood. Research in this area has suggested that obesity…

A Morphometric Assessment of the Influence of EGCG on Down Syndrome Facial Morphology. J Cintron, M Dierssen, R Gonzalez, J Sharpe, N Martinez-Abadias, J Starbuck.

Date: April 2019. Source: The FASEB Journal, Vol 33, No. 1_supplement. Abstract: Down syndrome (DS) is a genetic birth defect that results from Trisomy 21, which causes an overexpression of human chromosome 21 (HSA21) genes. Overexpressed HSA21 genes disturb development by altering morphogenesis and growth, resulting in cognitive impairment, characteristic facial morphology, and many other…

Cognitive Outcomes and Positional Plagiocephaly. BR Collett, ER Wallace, D Kartin, ML Cunningham, ML Speltz.

Date: February 2019. Source: Pediatrics, 143 (2) e20182373; DOI: https://doi.org/10.1542/peds.2018-2373. Background: Studies have revealed an association between positional plagiocephaly and/or brachycephaly (PPB) and development, although little is known about long-term outcomes. We examined cognition and academic achievement in children with and without PPB, testing the hypothesis that children who had PPB as infants would score…