Three-dimensional human facial morphologies as robust aging markers. W Chen, W Qian, G Wu, W Chen, B Xian, X Chen, Y Cao, CD Green, F Zhao, K Tang, JD Han.

Date: May 2015. Source: Journal of Cell Research, 25, 574-587. Abstract: Aging is associated with many complex diseases. Reliable prediction of the aging process is important for assessing the risks of aging-associated diseases. However, despite intense research, so far there is no reliable aging marker. Here we addressed this problem by examining whether human 3D…

Comparing Facial 3D Analysis With DNA Testing to Determine Zygosities of Twins. V Vuollo, M Sidlauskas, A Sidlauskas, V Harila, L Salomskiene, A Zhurov, L Holmström, P Pirttiniemi, T Heikkinen.

Date: June 2015. Source: Twin Research and Human Genetics, Volume 18, Issue 03, pp 306-313. Abstract: The aim of this study was to compare facial 3D analysis to DNA testing in twin zygosity determinations. Facial 3D images of 106 pairs of young adult Lithuanian twins were taken with a stereophotogrammetric device (3dMD, Atlanta, Georgia) and…

Monitoring of Therapy for Mucopolysaccharidosis Type I Using Dysmorphometric Facial Phenotypic Signatures. Stefanie Kung, M Walters, P Claes, P LeSouef, J Goldblatt, A Martin, S Balasubramaniam, G Baynam.

Date: March 2015. Source: JIMD Reports 2015, Springer. Abstract: There is a pattern of progressive facial dysmorphology in mucopolysaccharidosis type I (MPS I). Advances in 3D facial imaging have facilitated the development of tools, including dysmorphometrics, to objectively and precisely detect these facial phenotypes. Therefore, we investigated the application of dysmorphometrics as a noninvasive therapy-monitoring…

Prenatal sex hormones, digit ratio, and face shape in adult males. SM Weinberg, TE Parsons, ZD Raffensperger.

Date: February 2015. Source: Orthodontics & Craniofacial Research, 18(1):21-6. Objectives: Several reports have demonstrated a relationship between second to fourth digit ratio (2D:4D) and facial shape, suggesting that prenatal sex hormones play a role in the development of the craniofacial complex. Using 3D surface imaging and geometric morphometrics, we test the hypothesis that decreased digit…

Regional facial asymmetries in unilateral orofacial clefts. MA Kuijpers, DJ Desmedt, RM Nada, SJ Bergé, PS Fudalej, TJJ Maal.

Date: February 2015. Source: The European Journal of Orthodontics. Objectives: Assess facial asymmetry in subjects with unilateral cleft lip (UCL), unilateral cleft lip and alveolus (UCLA), and unilateral cleft lip, alveolus, and palate (UCLP), and to evaluate which area of the face is most asymmetrical. Methods: Standardized three-dimensional facial images of 58 patients (9 UCL,…

Monobloc Le Fort III Distraction Osteogenesis for Correction of Severe Fronto-orbital and Midface Hypoplasia in Pediatric Crouzon Syndrome. F Hariri, LK Cheung, ZA Rahman, V Mathaneswaran, D Ganesan.

Date: February 2015. Source: The Cleft Palate-Craniofacial Journal. Abstract: In severe syndromic craniosynostosis, distraction osteogenesis (DO) provides superior segmental advancement and allows progressive clinical monitoring to ensure that adequate skeletal expansion is achieved. We report two cases of Crouzon syndrome involving a 3-year-old boy and a 4-year-old girl, who were both treated with monobloc Le…

Quantitative Assessment of Facial Asymmetry Using Three-Dimensional Surface Imaging in Adults: Validating the Precision and Repeatability of a Global Approach. D Kornreich, AA Mitchell, BD Webb, I Cristian, EW Jabs.

Date: December 2014. Source: The Cleft Palate-Craniofacial Journal. Objective: Comparison of global versus landmark analyses of facial asymmetry using three-dimensional photogrammetry to establish a precise method for evaluating facial asymmetry. Design: The landmark-based approach utilized anthropometric data points. Our global approach involved registration of mirror images, independent of a midplane, to calculate a root mean…

The Latest Applications of Temporal-3D (4D) to Support Clinical Initiatives. CR Lane.

Date: October 2014. Source: 3D Body Scanning Conference 2014, Lugano, Switzerland. Abstract: In 2011 3dMD and the University of North Carolina at Chapel Hill, School of Dentistry, were awarded a ground-breaking US NIH Grant (STTR Grant No. 2R42DE019742-02) to study the facial dynamics of children who had received corrective treatment for facial conditions. The recruitment…