EDAR, LYPLAL1, PRDM16, PAX3, DKK1, TNFSF12, CACNA2D3, and SUPT3H gene variants influence facial morphology in a Eurasian population. Y Li, W Zhao, D Li et al.

Date: April 2019. Source: Human Genetics 138, 681–689 (2019). https://doi.org/10.1007/s00439-019-02023-7. Abstract: In human society, the facial surface is visible and recognizable based on the facial shape variation which represents a set of highly polygenic and correlated complex traits. Understanding the genetic basis underlying facial shape traits has important implications in population genetics, developmental biology, and…

MeshMonk: Open-source large-scale intensive 3D phenotyping. JD White, A Ortega-Castrillón, H Matthews et al.

Date: April 2019. Source: Scientific Reports 9, 6085. https://doi.org/10.1038/s41598-019-42533-y. Abstract: Dense surface registration, commonly used in computer science, could aid the biological sciences in accurate and comprehensive quantification of biological phenotypes. However, few toolboxes exist that are openly available, non-expert friendly, and validated in a way relevant to biologists. Here, we report a customizable toolbox…

Linking the Expression of Facial Shape and BMI via the Hippo Signaling Pathway. S Ali, DE Ehrlich, LM Moreno Uribe, BA Amendt, MK Lee, JR Shaffer, ML Marazita, SM Weinberg, SF Miller.

Date: April 2019. Source: The FASEB Journal, Vol. 33, No. 1_supplement. Abstract: Obesity rates have more than tripled in children and adolescents in recent years. While many studies have examined the relationship between obesity and chronic illnesses, the impact of obesity on craniofacial form is less understood. Research in this area has suggested that obesity…

A Morphometric Assessment of the Influence of EGCG on Down Syndrome Facial Morphology. J Cintron, M Dierssen, R Gonzalez, J Sharpe, N Martinez-Abadias, J Starbuck.

Date: April 2019. Source: The FASEB Journal, Vol 33, No. 1_supplement. Abstract: Down syndrome (DS) is a genetic birth defect that results from Trisomy 21, which causes an overexpression of human chromosome 21 (HSA21) genes. Overexpressed HSA21 genes disturb development by altering morphogenesis and growth, resulting in cognitive impairment, characteristic facial morphology, and many other…

Three-Dimensional Assessment of Morphological Changes Following Nasoalveolar Molding Therapy in Cleft Lip and Palate Patients: A Case Report. E Staderini, R Patini, A Camodeca, F Guglielmi, P Gallenzi.

Date: March 2019. Source: Dentistry Journal, 7(1), 27. Abstract: The applications of computer-guided technologies for three-dimensional image analysis provide a unique opportunity to quantify the morphological dimensional changes of the face in a practical and convenient way. Symmetry of the nasolabial area is one of the main factors of facial attractiveness as well as being…

Quantifying faces three-dimensionally in orthodontic practice. C Tanikawa, O Akcam, K Takada.

Date: March 2019. Source: Journal of Cranio-Maxillofacial Surgery (ONLINE). Objective: The purpose of this study was to formulate and demonstrate a method for quantifying and visualizing the three-dimensional (3-D) configuration of the soft tissues of the face at rest to facilitate a quantitative and instantaneous understanding of a patient’s static facial form characteristics. Materials and…

Combined use of a facial scanner and an intraoral scanner to acquire a digital scan for the fabrication of an orbital prosthesis. H Liu, S Bai, X Yu, Y Zhao.

Date: March 2019. Source: The Journal of Prosthetic Dentistry, Volume 121, Issue 3, Pages 531-534. Abstract: For a patient with a unilateral orbital defect, an esthetic orbital prosthesis plays an essential role in enhancing quality of life. This technique describes the combined use of a facial scanner and an intraoral scanner to acquire the digital…

Three-dimensional lip morphology in skeletal Class I malocclusion with labial inclination of the upper central incisors. M Sasaki, W Tome, A Takeuchi, N Kitai.

Date: March 2019. Source: Orthodontic Waves, Volume 78, Issue 1, Pages 33-38. Objective: The purpose of the present study was to examine the three-dimensional (3D) lip morphology in cases of skeletal Class I malocclusion with labial inclination of the upper central incisors. Materials and Methods: Thirty-five Japanese patients with malocclusion were divided into 2 groups:…

Lip position analysis of young women with different skeletal patterns during posed smiling using 3-dimensional stereophotogrammetry. H Li, T Cao, H Zhou, Y Hou.

Date: January 2019. Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 155, Issue 1, Pages 64-70. Highlights: • Posed smile, lip position, and skeletal patterns were investigated in young women. • Significant differences were found in interlabial gap and in the vertical, average, and horizontal groups. • Intercommissural width did not differ significantly among…