Exploratory genotype–phenotype correlations of facial form and asymmetry in unaffected relatives of children with non-syndromic cleft lip and/or palate. SF Miller, SM Weinberg, NL Nidey, DK Defay, ML Marazita, GL Wehby, LM Moreno Uribe.

3dMD Customer Research, Computer Science | Computer Vision, Dental, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, Oral and Maxillofacial, Orthodontics, Plastics, 3dMDface System

Date: June 2014 Source: Journal of Anatomy, Volume 224, Issue 6, pp 688-709. Abstract: Family relatives of children with nonsyndromic cleft lip with or without cleft palate (NSCL/P) who presumably carry a genetic risk yet do not manifest overt oral clefts, often present with distinct facial morphology of unknown genetic etiology. This study investigates distinct…

Reliability of Nasolabial Anthropometric Measures Using Three-Dimensional Stereophotogrammetry in Infants with Unrepaired Unilateral Cleft Lip. R Tse, L Booth, K Keys, B Saltzman, E Stuhaug, H Kapadia, C Heike.

3dMD Customer Research, Dental, Genetics, Medical, 3dMDface, 3dMDhead, Craniofacial/Cleft, Oral and Maxillofacial, Orthodontics, Plastics, 3dMDface System, 3dMDhead System

Date: April 2014 Source: Plastic & Reconstructive Surgery, Journal of the American Society of Plastic Surgery, Volume 133, Issue 4, p 530e–542e. Background: Surgical and orthodontic treatment of unilateral cleft lip +/– palate can produce dramatic changes in nasolabial form; however, the lack of ideal methods with which to objectively document three-dimensional form limits the…

Three-Dimensional Soft Tissue Change of the Malar Region with High Le-Fort 1 Advancement: Implications for Aesthetic Malar Contouring. D Morris, B Rosett, L Zhao, and P Patel.

3dMD Customer Research, Dental, Medical, 3dMDface, Craniofacial/Cleft, Oral and Maxillofacial, Plastics, 3dMDface System, 3dMDtrio System

Date: April 2014. Source: The Aesthetic Meeting 2014, San Francisco, USA. Abstract: While orthognathic procedures are performed for a number of clinical scenarios, a fundamental goal is to reposition the facial skeletal components so as to improve both function as well as aesthetics. For patients with malar hypoplasia, modification of the traditional Le Fort 1…

Modeling 3D Facial Shape from DNA. P Claes, DK Liberton, K Daniels, KM Rosana, EE Quillen, LN Pearson, B McEvoy, M Bauchet, AA Zaidi, W Yao, H Tang, GS Barsh, DM Absher, MD Shriver.

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, 3dMDface System, 3dMDtrio System

Date: March 2014 Source: PLOS Genetics. Abstract: Human facial diversity is substantial, complex, and largely scientifically unexplained. We used spatially dense quasi-landmarks to measure face shape in population samples with mixed West African and European ancestry from three locations (United States, Brazil, and Cape Verde). Using bootstrapped response-based imputation modeling (BRIM), we uncover the relationships…

The perception of facial asymmetry using 3-dimensional simulated images. G McAvinchey, F Maxim, B Nix, J Djordjevic, R Linklater, G Landini.

3dMD Customer Research, Dental, Medical, Psychology, 3dMDface, Craniofacial/Cleft, Oral and Maxillofacial, Orthodontics, Plastics, 3dMDface System

Date: March 2014. Source: The Angle Orthodontist (Online). Objective: To investigate the perception of facial asymmetry in young adults to identify the amounts of chin asymmetry that can be regarded as normal and may benefit from correction. Materials and Methods: Three-dimensional (3D) images of 56 individuals of mixed ethnicity were obtained and used to produce…

Digital imaging analysis to assess scar phenotype. BJ Smith, N Nidey, SF Miller, LMM Uribe, CL Baum, GS Hamilton, GL Wehby, M Dunnwald.

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Medical, 3dMDface, Morphometrics, Craniofacial/Cleft, Plastics, 3dMDface System

Date: March-April 2014. Source: Wound Repair and Regeneration, Volume 22, Issue 2, pages 228–238. Abstract: In order to understand the link between the genetic background of patients and wound clinical outcomes, it is critical to have a reliable method to assess the phenotypic characteristics of healed wounds. In this study, we present a novel imaging…

Stereophotogrammetry-Based Facial Depth Measurements, A Novel Method for Quantifying Facial Projection. YSN Jayaratne, CK Deutsch, RA Zwahlen.

3dMD Customer Research, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Craniofacial/Cleft, 3dMDface System

Date: February 2014. Source: Surgical Innovation, 21(1):59-64. Background: Orthognathic surgery leads to alteration of the spatial relationship of the mandible and maxilla resulting changes in the degree of facial projection. Traditional 2-dimensional cephalometry and photographic techniques do not provide data on facial depth. Though stereophotogrammetry can be used as a noninvasive method for evaluating facial…

3D asymmetry of operated children with oral clefts. I Bugaighis, CR Mattick, B Tiddeman, R Hobson.

3dMD Customer Research, Medical, 3dMDface, Craniofacial/Cleft, 3dMDface System

Date: February 2014. Source: Orthodontics & Craniofacial Research, 17(1):27-37. Objectives: To explore three-dimensional (3D) facial asymmetry differences in operated children with oral clefts and to compare the results with a control group. Setting and Sample Population: The sample comprised one hundred and three 8- to 12-year-old children: 40 with unilateral cleft lip and palate (UCLP); 23…

Three-Dimensional Stereophotogrammetry: A Novel Method in Volumetric Measurement of Infantile Hemangioma. DJJ Hermans, TJJ Maal, SJ Bergé, CJM Vleuten.

3dMD Customer Research, Dental, Medical, 3dMDface, 3dMDhead, Craniofacial/Cleft, Oral and Maxillofacial, Plastics, 3dMDface System, 3dMDhead System

Date: January 2014. Source: Pediatric Dermatology. Volume 31, Issue 1, pp 118-122. Abstract: Accurate and objective measurement of volume changes in infantile hemangiomas (IHs) is essential in routine clinical practice and clinical studies, particularly in the changing therapeutic landscape after the discovery of propranolol. Several bedside techniques for volume measurement have been described in the…

Detecting Genetic Association of Common Human Facial Morphological Variation Using High Density 3D Image Registration. S Peng, J Tan, S Hu, H Zhou, J Guo, L Jin, K Tang.

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, 3dMDface System

Date: December 2013. Source: PLoS Computational Biology, Public Library of Science. Abstract: Human facial morphology is a combination of many complex traits. Little is known about the genetic basis of common facial morphological variation. Existing association studies have largely used simple landmark-distances as surrogates for the complex morphological phenotypes of the face. However, this can…