The MC1R Gene and Youthful Looks. F Liu, MA Hamer, J Deelen, JS Lall, L Jacobs, D van Heemst, PG Murray, A Wollstein, AJM de Craen, HW Uh, CQ Zeng, A Hofman, AG Uitterlinden, JJ Houwing-Duistermaat, LM Pardo, M Beekman, PE Slagboom, T Nijsten, M Kayser, DA Gunn.

Date: April 2016. Source: Current Biology, Volume 26, Issue 9, 9 May 2016, Pages 1213–1220. Highlights: • We present the first genetic associations with how old people look (perceived age) • Variants in MC1R, a pigmentation gene, significantly associated with perceived age • The MC1R association was independent of wrinkling, skin color, and sun exposure…

Using the 3D Facial Norms Database to investigate craniofacial sexual dimorphism in healthy children, adolescents, and adults. MJ Kesterke, ZD Raffensperger, CL Heike, ML Cunningham, JT Hecht, CH Kau, NL Nidey, LM Moreno, GL Wehby, ML Marazita, and SM Weinberg.

Date: April 2016 Source: Biology of Sex Differences. Background: Although craniofacial sex differences have been extensively studied in humans, relatively little is known about when various dimorphic features manifest during postnatal life. Using cross-sectional data derived from the 3D Facial Norms data repository, we tested for sexual dimorphism of craniofacial soft-tissue morphology at different ages.…

Appealing Female Avatars from 3D Body Scans: Perceptual Effects of Stylization. R Fleming, BJ Mohler, J Romero, MJ Black, M Breidt.

Date: March 2016. Source: Semantic Scholar.org. Abstract: Advances in 3D scanning technology allow us to create realistic virtual avatars from full body 3D scan data. However, negative reactions to some realistic computer generated humans suggest that this approach might not always provide the most appealing results. Using styles derived from existing popular character designs, we…

Measuring Symmetry in Children With Unrepaired Cleft Lip: Defining a Standard for the Three-Dimensional Mid-facial Reference Plane. J Wu, C Heike, C Birgfeld, K Evans, M Maga, C Morrison, B Saltzman, L Shapiro, R Tse.

Date: March 2016 (Online ahead of print) Source: The Cleft Palate-Craniofacial Journal. Objective: Quantitative measures of facial form to evaluate treatment outcomes for cleft lip (CL) are currently limited. Computer-based analysis of three-dimensional (3D) images provides an opportunity for efficient and objective analysis. The purpose of this study was to define a computer-based standard of…

Molecular genetic analysis in 14 czech kabuki syndrome patients is confirming the utility of phenotypic scoring. J Paděrová; A Holubová; M Simandlová; A Puchmajerová; M Vlčková; M Malíková; R Pourová; S Vejvalková; M Havlovicová; M Šenkeříková; N Ptáková; J Drábová; J Geryk; A Maver; A Křepelová; M Macek.

Date: February 2016. Source: Clinical Genetics. The International Journal of Genetics, Molecular, and Personalized Medicine. Abstract: Kabuki syndrome (KS) is a dominantly inherited disorder mainly due to de novo pathogenic variation in KMT2D or KDM6A genes. Initially, a representative cohort of 14 Czech cases with clinical features suggestive of KS was analyzed by experienced clinical…

Facial morphology in children and adolescents with juvenile idiopathic arthritis and moderate to severe temporomandibular joint involvement. YJ Hsieh, TA Darvann, NV Hermann, P Larsen, YF Liao, J Bjoern-Joergensen, S Kreiborg.

Date: February 2016 Source: American Journal of Orthodontics & Dentofacial Orthopedics. Volume 149, Issue 2, Pages 182–191. Highlights: • We evaluated lateral facial morphology of juvenile idiopathic arthritis patients with moderate and severe TMJ involvement. • Differences in their lateral facial morphologies between unilateral and bilateral TMJ involvement were also assessed. Introduction: The aims of…

Measuring Symmetry in Children With Cleft Lip. Part 2: Quantification of Nasolabial Symmetry Before and After Cleft Lip Repair. J Wu, S Liang, L Shapiro, R Tse.

Date: December 2015. Source: The Cleft Palate-Craniofacial Journal. Objective: The first part of this study validated an automated computer-based method of identifying the three-dimensional midfacial plane in children with unrepaired cleft lip. The purpose of this second part is to develop computer-based methods to quantify symmetry and to determine the correlation of these measures to…

Regional facial asymmetries and attractiveness of the face. AE Kaipainen, KR Sieber, RM Nada, TJ Maal, C Katsaros, PS Fudalej.

Date: December 2015 Source: The European Journal of Orthodontics. Objective: Facial attractiveness is an important factor in our social interactions. It is still not entirely clear which factors influence the attractiveness of a face and facial asymmetry appears to play a certain role. The aim of the present study was to assess the association between…

Application of Computer-Assisted Design and Manufacture in Unilateral Alloplastic Microtia Reconstruction, H Chen, ZC Chen.

Date: September 17, 2015. Source: 16th Congress of International Society of Craniofacial Surgery (ISCFS) 2015. Presenter: Hsin-Yu Chen. Background: The advances in 3D scanning, computer-assisted design and manufacture (CAD/CAM), and rapid-prototyping technology make customizing a symmetric auricular framework feasible for unilateral microtia patients. In this study, we used an active stereo-photogrammetry system to acquire the…

A Morphable Profile Model of the Human Head as an Outcome Tool for Craniosynostosis Surgery, C Duncan, R Armstrong, NE Pears.

Date: September 15, 2015. Source: 16th Congress of International Society of Craniofacial Surgery (ISCFS) 2015. Presenter: C Duncan. Introduction: Outcome analysis in craniosynostosis surgery is difficult and often relies on limited anthropometric measurement, qualitative analysis of photography or patient reported outcome. Quantifiable morphable models of the human face have been described but, to date, a…