Exploratory genotype–phenotype correlations of facial form and asymmetry in unaffected relatives of children with non-syndromic cleft lip and/or palate. SF Miller, SM Weinberg, NL Nidey, DK Defay, ML Marazita, GL Wehby, LM Moreno Uribe.

Date: June 2014 Source: Journal of Anatomy, Volume 224, Issue 6, pp 688-709. Abstract: Family relatives of children with nonsyndromic cleft lip with or without cleft palate (NSCL/P) who presumably carry a genetic risk yet do not manifest overt oral clefts, often present with distinct facial morphology of unknown genetic etiology. This study investigates distinct…

Modeling 3D Facial Shape from DNA. P Claes, DK Liberton, K Daniels, KM Rosana, EE Quillen, LN Pearson, B McEvoy, M Bauchet, AA Zaidi, W Yao, H Tang, GS Barsh, DM Absher, MD Shriver.

Date: March 2014 Source: PLOS Genetics. Abstract: Human facial diversity is substantial, complex, and largely scientifically unexplained. We used spatially dense quasi-landmarks to measure face shape in population samples with mixed West African and European ancestry from three locations (United States, Brazil, and Cape Verde). Using bootstrapped response-based imputation modeling (BRIM), we uncover the relationships…

The cluster assessment of facial attractiveness using fuzzy neural network classifier based on 3D Moiré features. WC Chiang, HH Lin, CS Huang, LJ Lo, SY Wan.

Date: March 2014. Source: Pattern Recognition. Volume 47, Issue 3, pp 1249–1260. Abstract: Facial attractiveness has long been argued upon varied emphases by philosophers, artists, psychologists and biologists. A number of studies empirically investigated how facial attractiveness was influenced by 2D facial characteristics, such as symmetry, averageness and golden ratio. However, few implementations of facial…

Stereophotogrammetry-Based Facial Depth Measurements, A Novel Method for Quantifying Facial Projection. YSN Jayaratne, CK Deutsch, RA Zwahlen.

Date: February 2014. Source: Surgical Innovation, 21(1):59-64. Background: Orthognathic surgery leads to alteration of the spatial relationship of the mandible and maxilla resulting changes in the degree of facial projection. Traditional 2-dimensional cephalometry and photographic techniques do not provide data on facial depth. Though stereophotogrammetry can be used as a noninvasive method for evaluating facial…

Detecting Genetic Association of Common Human Facial Morphological Variation Using High Density 3D Image Registration. S Peng, J Tan, S Hu, H Zhou, J Guo, L Jin, K Tang.

Date: December 2013. Source: PLoS Computational Biology, Public Library of Science. Abstract: Human facial morphology is a combination of many complex traits. Little is known about the genetic basis of common facial morphological variation. Existing association studies have largely used simple landmark-distances as surrogates for the complex morphological phenotypes of the face. However, this can…

BBC: Defining the most 'normal' shape of a human skull.

Date: 22 November 2013 Source: BBC News Article: Defining the most ‘normal’ shape of a human skull Reconstructive surgery for people born with a misshapen skull is one of medicine’s most complicated challenges. Part of the problem for surgeons is defining what a normal head actually looks like.  A team of Liverpool-based surgeons, and artists,…

Be Part of the Alder Hey Children’s Hospital Headspace Project and Change Lives!

Liverpool, United Kingdom (24-September-13): Alder Hey Children’s Hospital and FACT are looking for volunteers to take part in a groundbreaking project which will impact on the future development of craniofacial surgery. The Headspace project, created by Alder Hey in conjunction with FACT and associated artists will develop a comprehensive database of human head shapes using…

Comparison of facial morphologies between adult Chinese and Houstonian Caucasian populations using three-dimensional imaging. J Wirthlin, CH Kau, JD English, F Pan, H Zhou.

Date: Sep 2013 Source: International Journal of Oral and Maxillofacial Surgery, 42(9):1100-7. Abstract: The objective of this study was to compare the facial morphologies of an adult Chinese population to a Houstonian white population. Three-dimensional (3D) images were acquired via a commercially available stereophotogrammetric camera system, 3dMDface™. Using the system, 100 subjects from a Houstonian…

Improved Detection of Landmarks on 3D Human Face Data. S Liang; S Weinberg; L Shapiro.

Date: July 2013. Source: IEEE Engineering in Medicine and Biology Society Annual Conference. Abstract: Craniofacial researchers make heavy use of established facial landmarks in their morphometric analyses. For studies on very large facial image datasets, the standard approach of manual landmarking is very labor intensive. With the goal of producing 20 established landmarks, we have…

The Use of Pseudo-landmarks for Craniofacial Analysis: A Comparative Study with L1 Regularized Logistic Regression. E Mercan; L Shapiro; S Weinberg; SI Lee.

Date: July 2013. Source: IEEE Engineering in Medicine and Biology Society Annual Conference. Abstract: Morphometrics, the quantitative analysis of shape, is used by craniofacial researchers to study abnormalities in human face shapes. Most of the work in craniofacial morphometrics uses landmark points that are manually marked on 3D face data and processed via a generalized…