Genetic and Environmental Contributions to Facial Morphological Variation: A 3D Population-Based Twin Study. J Djordjevic, AI Zhurov, S Richmond, Visigen Consortium.

3dMD Customer Research, Computer Science | Computer Vision, Dental, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, Orthodontics, 3dMDface System

Date: September 2016 Source: PLoS One. 11(9):e0162250. Introduction: Facial phenotype is influenced by genes and environment; however, little is known about their relative contributions to normal facial morphology. The aim of this study was to assess the relative genetic and environmental contributions to facial morphological variation using a three-dimensional (3D) population-based approach and the classical…

Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. JR Shaffer, E Orlova, MK Lee, EJ Leslie, ZD Raffensperger, CL Heike, more…

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, 3dMDface System

Date: August 2016 Source: PLOS Genetics Abstract: Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet little is known about how specific genetic variants relate to the phenotypic expression of many common facial features. We conducted genome-wide association meta-analyses of 20 quantitative facial measurements derived from the 3D surface…

Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping. D Tsagkrasoulis, P Hysi, T Spector, G Montana.

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, 3dMDface System

Date: August 2016 Source: ResearchGate Abstract: The human face is a complex trait under strong genetic control, as evidenced by the striking visual similarity between twins. Nevertheless, heritability estimates of facial traits have often been surprisingly low or difficult to replicate. Furthermore, the construction of facial phenotypes that correspond to naturally perceived facial features remains…

Multiscale Mechano-Biological Finite Element Modelling of Oncoplastic Breast Surgery—Numerical Study towards Surgical Planning and Cosmetic Outcome Prediction. Vavourakis V, Eiben B, Hipwell JH, Williams NR, Keshtgar M, Hawkes DJ.

3dMD Customer Research, Computer Science | Computer Vision, Human Factors | Anthropometric, Medical, Anthropometric, Morphometrics, Plastics, 3dMDtorso System, 3dMDthorax

Date: July 2016 Source: PLoS ONE 11(7): e0159766. Abstract: Surgical treatment for early-stage breast carcinoma primarily necessitates breast conserving therapy (BCT), where the tumour is removed while preserving the breast shape. To date, there have been very few attempts to develop accurate and efficient computational tools that could be used in the clinical environment for…

Hypertelorism and Orofacial Clefting Revisited: An Anthropometric Investigation. SM Weinberg, EJ Leslie, JT Hecht, GL Wehby, FWB Deleyiannis, LM Moreno, K Christensen, ML Marazita.

3dMD Customer Research, Computer Science | Computer Vision, Dental, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, Orthodontics, Plastics, 3dMDface System

Date: June 2016. ONLINE AHEAD OF PRINT Source: The Cleft Palate-Craniofacial Journal. Objective: Since the 1960s, multiple studies have reported a tendency toward hypertelorism in individuals with nonsyndromic orofacial clefts (OFCs). However, the association between specific cleft types and increased interorbital distance has been inconsistent. Using three-dimensional (3D) surface imaging, we tested whether different forms…

Measuring Symmetry in Children With Unrepaired Cleft Lip: Defining a Standard for the Three-Dimensional Mid-facial Reference Plane. J Wu, C Heike, C Birgfeld, K Evans, M Maga, C Morrison, B Saltzman, L Shapiro, R Tse.

3dMD Customer Research, Computer Science | Computer Vision, Dental, Genetics, Human Factors | Anthropometric, Medical, 3dMDhead, Anthropometric, Morphometrics, Craniofacial/Cleft, Oral and Maxillofacial, Orthodontics, Orthognathic, Plastics, Static 3D Systems, 3dMDhead System

Date: March 2016 (Online ahead of print) Source: The Cleft Palate-Craniofacial Journal. Objective: Quantitative measures of facial form to evaluate treatment outcomes for cleft lip (CL) are currently limited. Computer-based analysis of three-dimensional (3D) images provides an opportunity for efficient and objective analysis. The purpose of this study was to define a computer-based standard of…

Measuring Symmetry in Children With Cleft Lip. Part 2: Quantification of Nasolabial Symmetry Before and After Cleft Lip Repair. J Wu, S Liang, L Shapiro, R Tse.

3dMD Customer Research, Computer Science | Computer Vision, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, 3dMDface System

Date: December 2015. Source: The Cleft Palate-Craniofacial Journal. Objective: The first part of this study validated an automated computer-based method of identifying the three-dimensional midfacial plane in children with unrepaired cleft lip. The purpose of this second part is to develop computer-based methods to quantify symmetry and to determine the correlation of these measures to…

Evaluating 3-Dimensional Soft Tissue Changes in Class III Chinese Patients after Orthognathic Surgery. JX Su, M Yow, MT Chew, HC Wong.

3dMD Customer Research, Computer Science | Computer Vision, Dental, Medical, 3dMDface, Morphometrics, Craniofacial/Cleft, Multimodal (CT/CBCT), Oral and Maxillofacial, Orthodontics, 3dMDface System

Date: September 2015. Source: 8th International Orthodontic Congress 2015, London. Aim: To evaluate facial soft tissue changes in Class III skeletal Chinese patients who have undergone orthognathic surgery. Objective. To determine if there is a correlation between hard and soft tissue movement after orthognathic surgery. Study Design: This is a retrospective study involving 15 Chinese…

A Morphable Profile Model of the Human Head as an Outcome Tool for Craniosynostosis Surgery, C Duncan, R Armstrong, NE Pears.

3dMD Customer Research, Computer Science | Computer Vision, Human Factors | Anthropometric, Medical, 3dMDhead, Anthropometric, Computer Science, Morphometrics, Craniofacial/Cleft, Plastics, Prosthetics, 3dMDhead System

Date: September 15, 2015. Source: 16th Congress of International Society of Craniofacial Surgery (ISCFS) 2015. Presenter: C Duncan. Introduction: Outcome analysis in craniosynostosis surgery is difficult and often relies on limited anthropometric measurement, qualitative analysis of photography or patient reported outcome. Quantifiable morphable models of the human face have been described but, to date, a…