Date: October 2014. Source: 3D Body Scanning Conference 2014, Lugano, Switzerland. Abstract: In 2011 3dMD and the University of North Carolina at Chapel Hill, School of Dentistry, were awarded a ground-breaking US NIH Grant (STTR Grant No. 2R42DE019742-02) to study the facial dynamics of children who had received corrective treatment for facial conditions. The recruitment…
Date: October 2014. Source: 3D Body Scanning Conference 2014, Lugano, Switzerland. Abstract: Facial biometrics as an objective, accurate, living parts measurement methodology, is widely used in assisting diagnose and treatment plan within the practice of medicine and dentistry. It is particularly popular that the quantification of changes before and after a clinical intervention. However the…
Date: October 2014. Source: Artificial Intelligence in Medicine, 62(2):105-18. Background: In general, medical geneticists aim to pre-diagnose underlying syndromes based on facial features before performing cytological or molecular analyses where a genotype–phenotype interrelation is possible. However, determining correct genotype–phenotype interrelationships among many syndromes is tedious and labor-intensive, especially for extremely rare syndromes. Thus, a computer-aided…
Date: August 2014. Source: Int. Conference on Pattern Recognition (ICPR) 2014, Stockholm, Sweden. © IEEE. Pages 460-464. Abstract: Cleft lip is a birth defect that results in deformity of the upper lip and nose. Its severity is widely variable and the results of treatment are influenced by the initial deformity. Objective assessment of severity would…
Date: June 2014. Source: International Journal of Morphology. Volume 32, Number 2, pp 499–509. Summary: Morphometric approaches can be combined with 2D or 3D imaging to quantitatively evaluate craniofacial medical conditions depicted in material culture and to learn more about the culture being studied. A terra-cotta figurine (circa 500 A.D.) from the Tolteca culture of…
Date: June 2014 Source: Journal of Anatomy, Volume 224, Issue 6, pp 688-709. Abstract: Family relatives of children with nonsyndromic cleft lip with or without cleft palate (NSCL/P) who presumably carry a genetic risk yet do not manifest overt oral clefts, often present with distinct facial morphology of unknown genetic etiology. This study investigates distinct…
Date: April 2014 Source: Plastic & Reconstructive Surgery, Journal of the American Society of Plastic Surgery, Volume 133, Issue 4, p 530e–542e. Background: Surgical and orthodontic treatment of unilateral cleft lip +/– palate can produce dramatic changes in nasolabial form; however, the lack of ideal methods with which to objectively document three-dimensional form limits the…
Date: March 2014 Source: PLOS Genetics. Abstract: Human facial diversity is substantial, complex, and largely scientifically unexplained. We used spatially dense quasi-landmarks to measure face shape in population samples with mixed West African and European ancestry from three locations (United States, Brazil, and Cape Verde). Using bootstrapped response-based imputation modeling (BRIM), we uncover the relationships…
Date: March-April 2014. Source: Wound Repair and Regeneration, Volume 22, Issue 2, pages 228–238. Abstract: In order to understand the link between the genetic background of patients and wound clinical outcomes, it is critical to have a reliable method to assess the phenotypic characteristics of healed wounds. In this study, we present a novel imaging…
Date: January 2014 Source: Comprehensive Guide to Autism, pp 2853–2880. New York: Springer, 2014. Abstract: Many common human neurological disorders, including autism spectrum disorder (ASD), epilepsy, Alzheimer’s disease, attention-deficit/hyperactivity disorder (ADHD), and schizophrenia, have complex genetics and inheritance patterns. While understanding the molecular mechanisms of single-gene disorders is comparatively straightforward, complex diseases are, by their…