Detecting Genetic Association of Common Human Facial Morphological Variation Using High Density 3D Image Registration. S Peng, J Tan, S Hu, H Zhou, J Guo, L Jin, K Tang.

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Human Factors | Anthropometric, Medical, 3dMDface, Anthropometric, Morphometrics, Craniofacial/Cleft, 3dMDface System

Date: December 2013. Source: PLoS Computational Biology, Public Library of Science. Abstract: Human facial morphology is a combination of many complex traits. Little is known about the genetic basis of common facial morphological variation. Existing association studies have largely used simple landmark-distances as surrogates for the complex morphological phenotypes of the face. However, this can…

Indiana University visualization experts help doctors diagnose fetal alcohol spectrum disorders with 3dMD

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Date: October 10, 2013 Source: Indiana University, IT News & Events BLOOMINGTON, Ind. — Indiana University received a $125,000 grant renewal from the National Institutes of Health for ongoing research into detecting fetal alcohol spectrum disorders, a leading but preventable cause of birth defects. IU has been engaged in the Collaborative Initiative on Fetal Alcohol…

Automated Three Dimensional (3D) Measures of the Static Face in Normal and Dysmorphic Conditions: Novel Technology for Facial Measurement. CA Trotman, C Heaston, C Phillips, A Mercado, N Lee, T Hartman.

3dMD Customer Research, Computer Science | Computer Vision, Dental, Genetics, Human Factors | Anthropometric, Medical, Psychology, 3dMDface, Anthropometric, Computer Science, Morphometrics, Craniofacial/Cleft, Oral and Maxillofacial, Orthodontics, 3dMDface System, Temporal-3D Systems (4D)

Date: May 2013 Source: 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies, Lake Buena Vista, Florida Abstract: #1772 Authors: CA Trotman, C Heaston, C Phillips, A Mercado, N Lee, T Hartman. School of Dentistry, University of North Carolina at Chapel Hill, USA.

3D Imaging and Informatics Approaches to Diagnose Genetic Conditions. C Deutsch.

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Date: April 2013. Source: 2013 Bio-IT World Conference & Expo; Boston, USA. Abstract: With the support of NIH, we have developed the first quantitative normative database to diagnose craniofacial abnormalities. This new informatics resource, combined with novel methods in 3D surface imaging and 3D morphometry, provides the means of defining features of medical genetic conditions.…

Soft-Tissue Volumetric Changes Following Monobloc Distraction Procedure: Analysis Using Digital Three-Dimensional Photogrammetry System (3dMD). FC Chan, HK Kawamoto, C Federico, JP Bradley.

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Date: March 2013. Source: Journal of Craniofacial Surgery, Volume 24, Issue 2, pp 416-420. Abstract: We have previously reported that monobloc advancement by distraction osteogenesis resulted in decreased morbidity and greater advancement with less relapse compared with acute monobloc advancement with bone grafting. In this study, we examine the three-dimensional (3D) volumetric soft-tissue changes in…

Trisomy 21 and Facial Developmental Instability. JM Starbuck, TM Cole III, RH Reeves, and JT Richtsmeier.

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Date: February 2013. Source: American Journal of Physical Anthropology, Volume 151, Issue 1, pp 49-57. Abstract: The most common live-born human aneuploidy is trisomy 21, which causes Down syndrome (DS). Dosage imbalance of genes on chromosome 21 (Hsa21) affects complex gene-regulatory interactions and alters development to produce a wide range of phenotypes, including characteristic facial dysmorphology. Little is known about how…

The facial evolution: looking backward and moving forward. G Baynam, M Walters, P Claes, S Kung, P LeSouef, H Dawkins, D Gillett, J Goldblatt.

3dMD Customer Research, Computer Science | Computer Vision, Genetics, Human Factors | Anthropometric, Anthropometric, Morphometrics, 3dMDface System

Date: January 2013. Source: Human Mutation; 34(1): pp 14-22. Abstract: Three-dimensional (3D) facial analysis is ideal for high-resolution, nonionizing, noninvasive objective, high-throughput phenotypic, and phenomic studies. It is a natural complement to (epi)genetic technologies to facilitate advances in the understanding of rare and common diseases. The face is uniquely reflective of the primordial tissues, and…

Relation Over Time Between Facial Measurements and Cognitive Outcomes in Fetal Alcohol-Exposed Children. T Foroud, L Wetherill, S Vinci-Booher, ES Moore, RE Ward, HE Hoyme, LK Robinson, J Rogers, EM Meintjes, CD Molteno, JL Jacobson, SW Jacobson.

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Date: September 2012. Source: Alcoholism: Clinical and Experimental Research, Volume 36, Issue 9, pages 1634–1646, September 2012. Background: The identification of individuals exposed prenatally to alcohol can be challenging, with only those having the characteristic pattern of facial features, central nervous system abnormality, and growth retardation receiving a clinical diagnosis of fetal alcohol syndrome (FAS).…

BBC Health. 3D Face Scan to Help Future Surgery.

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Date: January 2012. Source: BBC Health. 3D face scan to help future surgery Article: Visitors to London’s Science Museum are being invited to have their faces scanned in 3D. The ‘Me in 3D’ exhibit uses an array of cameras to build a virtual image visitors can then view and manipulate. Data from the participants will…